Publications

Department of Chemistry and Biochemistry

Baylor university

2017

Abdolvahabi A, Shi Y, Rasouli S, Croom CM, Aliyan A, Marti AA, Shaw BF. Kaplan-Meier meets chemical kinetics: intrinsic rate of SOD1 amyloidogenesis decreased by subset of ALS mutations and cannot fully explain age of disease onset. ACS Chem. Neurosci., 2017, March 14; [Epub ahead of print].

Abdolvahabi A, Shi Y, Rasouli S, Croom CM, Chuprin A, Shaw BF. How Do Gyrating Beads Accelerate Amyloid Fibrillization? Biophys J. 2017 Jan 24;112(2):250-264.

2016

Shi, Y., Acerson, M.J., Abdolvahabi, A, Mowery, R.A., Shaw B.F. Gibbs energy of superoxide dismutase heterodimerization accounts for variable survival in amyotrophic lateral sclerosis. J Am Chem Soc. 2016 Apr 27;138(16):5351-62

Abdolvahabi A, Shi Y, Chuprin A, Rasouli S, Shaw BF. Stochastic formation of fibrillar and amorphous superoxide dismutase oligomers linked to amyotrophic lateral sclerosi. ACS Chem Neurosci. 2016 Jun 15;7(6):799-810

2015

Shi, Y., Acerson, M. J., Shuford, K. L. & Shaw, B. F. Voltage induced misfolding of zinc replete ALS mutant superoxide dismutase-1. ACS Chem. Neurosci., 2015, Oct 21;6(10):1696-707

Sea, K.; Sohn, S. H.; Durazo, A.; Sheng, Y.; Shaw, B. F.; Cao, X.; Taylor, A. B.; Whitson, L. J.; Holloway, S. P.; Hart, P. J.; Cabelli, D. E.; Gralla, E. B.; Valentine, J. S. Insights into the role of the unusual disulfide bond in copper-zinc superoxide dismutase. J. Biol. Chem., 2015, 290, 2405-2418.


Abdolvahabi, A.; Shi, Y.; Rhodes, N. R.; Cook, N. P.; Marti, A. A.; Shaw, B. F. Arresting Amyloid with Coulomb's Law: Acetylation of ALS-Linked SOD1 by Aspirin Impedes Aggregation. Biophys J. 2015, 108, 1199-212.

2014

Abdolvahabi, A., Gober, J. L., Mowery, R. A., Shi, Y. & Shaw, B. F. Metal Ion-Specific Screening of Charge Effects in Protein Amide H/D Exchange Follows the Hofmeister Series. Anal Chem. 2014,86, 10303-10.


Rivas-Perea, P., Baker, E., Hamerly, G. & Shaw, B. F. Detection of leukocoria using a soft fusion of expert classifiers under non-clinical settings. BMC Ophthalmol. 2014; 14, 110.


Shi, Y., Abdolvahabi, A. & Shaw, B. F. Protein charge ladders reveal that the net charge of ALS-linked superoxide dismutase can be different in sign and magnitude from predicted values. Protein Sci. 2014, [Epub ahead of print].

2013

7) Shi Y, Rhodes NR, Abdolvahabi A, Kohn T, Cook NP, Marti AA, Shaw BF. Deamidation of Asparagine to Aspartate Destabilizes Cu, Zn Superoxide Dismutase, Accelerates Fibrillization, and Mirrors ALS-Linked Mutations. J Am Chem Soc. 2013;135(42):15897-908.


Abdolvahabi, A., Taylor B.W., Holden R.L., Shaw E.V., Kentsis A., Rodriguez-Galindo C., Mukai S., Shaw, B.F. Colorimetric and Longitudinal Analysis of Leukocoria in Recreational Photographs of Children with Retinoblastoma. PLoS ONE. 2013


Shi Y, Mowery RA, Shaw BF. Effect of Metal Loading and Subcellular pH on Net Charge of Superoxide Dismutase-1. J Mol Biol. 2013;425(22):4388-404


Alves, N.J., Champion, M.M., Stefanick, J.F., Handlogten, M.W., Moustakas, D.T., Shi, Y., Shaw, B.F., Navari, R.M., Kiziltepe, T., Bilgicer, B. Selective photocrosslinking of functional ligands to antibodies via the conserved nucleotide binding site. Biomaterials. 2013; 34(22): 5700-5710.


Krishnamurthy, V.J., Raman, V.S., Mowery, R.A., Hentz, M., Balega, J.D., Shaw, B.F., Kumar, K. Ligand-Induced Protein Mobility in Complexes of Carbonic Anhydrase II and Benzenesulfonamides with Oligoglycine Chains. PLoS ONE. 2013; 8(3): e57629.

2012

Shi Y., Mowery R.A., Ashley J., Hentz M., Ramirez A.J., Bilgicer B., Slunt-Brown H., Borchelt D.R., Shaw B.F.* Abnormal SDS-PAGE migration of cytosolic proteins can identify domains and mechanisms that control surfactant binding. Protein Sci. 2012; 21(8):1197-1209.

Shaw, B.F.*, Schneider, G.F., Whitesides, G.M.* Effect of Surfactant Hydrophobicity on the Pathway for Unfolding of Ubiquitin J. Am. Chem. Soc. 2012; 134(45):18739-18745.
(*BFS co-corresponding author with George M. Whitesides)

2011

Shaw, B.F.*, Schneider, G.F., Arthanari, H., Narovlyansky, M., Moustakas, D., Durazo, A., Wagner, G., Whitesides, G.M.* Complexes of native Ubiquitin and dodecyl sulfate illustrate the nature of hydrophobic and electrostatic interactions in the binding of proteins and surfactants. J. Am. Chem. Soc. 2011; 133(44): 17681-17695.
(*BFS co-corresponding author with George M. Whitesides)

2010

Shaw, B.F.*, Arthanari, H., Lee, A., Durazo, A., Frueh, D.P., Pollastri, M.P., Bilgicer, B., Gygi, S.P., Wagner, G., Whitesides, G.M.* Neutralizing positive charges at the surface of a protein lowers its rate of amide H/D exchange without altering its structure or raising its thermostability. J. Am. Chem. Soc. 2010; 132 (49): 17411-17425

(*BFS co-corresponding author with George M. Whitesides)

2009

Bilgicer, B., Thomas, S.W., Shaw, B.F., Kaufman, G.K., Krishnamurthy, V.M., Estroff, L.A., Whitesides, G.M. A non-chromatographic method for the purification of a bivalent monoclonal IgG antibody from biological fluid. J. Am. Chem. Soc. 2009; 131(26): 9361-7.


Durazo, A., Shaw, B.F., Chattopadhyay, M., Faull, K.F., Valentine, J.S., Whitelegge, J.P. Metal free wild-type superoxide dismutase-1 and three different ALS variants share a similar partially unfolded β-barrel at physiological temperature. J. Biol. Chem. 2009; 284(49): 34382-9.


Kaufman, G.K., Thomas, S.W., Reches, M., Feng, J., Shaw, B.F., Whitesides, G.M. Phase separation of 2D Coulombic crystals of meso-scale dipolar particles from meso-scale polarizable “solvent.” App. Phys. Lett. 2009; 94 (4): 44102.


Kaufman, G.K., Thomas, S.W., Reches, M., Shaw, B.F., Feng, J., Whitesides, G.M. Phase separation of 2D meso-scale Coulombic crystals from meso-scale polarizable “solvent.” Soft Matter 2009; 5: 1188-1191.


Durer, Z., Cohlberg, J.A., Dinh, P., Padua, S., Ehrenclou, K., Downes, S., Tan, J.K., Nakano, Y., Bowman, C.J., Rosales, J., Hoskins, J.L., Kwon, C., Mason, A.Z., Rodriguez, J.A., Doucette, P.A., Shaw, B.F., Valentine, J.S. Loss of metal ions, disulfide reduction and mutations related to familial ALS promote amyloid formation from superoxide dismutase. PLoS ONE 2009; 4(3): e5004.

2008

Shaw, B.F., Schneider, G.F., Bilgicer, B., Kaufman, G.K., Neveu, J.M., Lane, W.S., Whitelegge, J.P., Whitesides, G.M. Lysine acetylation can generate highly charged enzymes with increased resistance towards irreversible inactivation. Protein Sci. 2008; 17(8): 1446-1455.